OFF-LABEL PHARMACEUTICAL USE


OFF-LABEL PHARMACEUTICAL USE

According to NIH, there are almost 7,000 identified distinct rare diseases, the vast majority of which are genetic in nature. The Orphan Drug Act of 1983 has been a landmark success at making the development of orphan products a profitable venture, thereby driving industry to invest in research and development for rare disease treatments. To date, some 2,200 investigational therapies have been designated “orphan drugs” by FDA’s Office of Orphan Products Development, and 360 of these have gone on through the review process to be approved for marketing.
The approval of 360 drugs is a huge step in the right direction for the rare disease community. However, these drugs are indicated for only about 200 rare diseases, leaving approximately 6,800 diseases without FDA-approved treatment. In other words,

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Topic: 5 ways to ward off the winter blues


5 ways to ward off the winter blues

It’s that time of year again. The holidays are over and the next few months seem to offer nothing to look forward to but gloomy grey skies, bone-chilling weather, and piles of snow. It’s no wonder why many people suffer symptoms similar to those of depression, such as sadness, fatigue, and irritability during these long winter months.

If you don’t have the luxury of escaping to a warm tropical island until April, there are other more feasible ways to beat the winter blues.

Exercise

With a lack of sunshine to keep you energized, it’s tempting to want to spend your evenings hibernating under the covers instead of being active. But remember, exercise is known to increase your levels of serotonin and endorphins, leading to a happier mood. While it’s understandable that many people are less than keen about participating in outdoor activities during these chilly months, keep in mind that there are many ways to keep active while staying indoors. Join a gym class, walk on the treadmill while watching TV, or try out a new lively game on Wii.

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http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12779760-5-ways-to-ward-off-the-winter-blues

AMA Agrees Marijuana May Have Analgesic Benefits


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AMA Agrees Marijuana May Have Analgesic Benefits This article is reprinted from the blog Pain-Topics.org The American Medical Association (AMA) has reversed its long-held position that marijuana should remain as a DEA Schedule I substance having no medical value. Rescheduling of the drug could open the door to more and better scientific exploration of its benefits in helping persons with various pain conditions. In its recently-announced decision, the AMA adopted a report drafted by its Council on Science and Public Health (CSAPH) entitled, “Use of Cannabis for Medicinal Purposes,”

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http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12779625-ama-agrees-marijuana-may-have-analgesic-benefits-

5 Myths About Panic Disorders


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5 Myths About Panic Disorders

Panic attacks are frightening and disruptive enough; you don’t need the additional stress of worrying about whether common misconceptions about panic disorders are true.
Panic disorders cause sudden and repeated attacks of fear despite the absence of any real danger. Although panic attacks can seem interminable at the time, an attack generally lasts only a few minutes. About six million adults suffer from panic disorders. They generally begin in individuals’ late teens or early adulthood years, and women are more likely than men to experience them.

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http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12777581-5-myths-about-panic-disorders

Acupressure for Pain


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Acupressure for Pain

Acupressure is a part of Chinese Medicine to treat some of the conditions like back pain, neck pain, etc. by applying pressure to different parts of the body known as acupressure points. Acupressure is safe and gentle.
Acupressure points are places on the skin that are especially sensitive to bio-electrical impulses in the body. Stimulating these points with pressure, needles, or heat triggers the release of endorphins that relieve pain. Acupressure inhibits the pain signals that are transmitted to the brain preventing painful sensations from passing through the spinal cord to the brain. As a result, pain is blocked and the flow of blood and oxygen to the affected area is increased.

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Advocacy Tips for Family Caregivers


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A Call to Action
Families—not institutions—provide the majority of care to chronically ill and disabled loved ones. These families know the enormity of the burden in caring for someone with Alzheimer’s or Parkinson’s diseases, stroke, traumatic brain injury, or other long-term conditions. They also know the challenges in locating appropriate advice, services and respite.
Personal experience with community agencies, round-the-clock care, and financial hardships mean families know what the important issues are. This puts family caregivers in a unique position to act as advocates. Caregivers can educate elected officials charged with development of public policy and funding priorities.

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http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12777346-advocacy-tips-for-family-caregivers

Adhesion Pain

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Adhesion Pain

Doctors: Bound by Secrecy? Victims: Bound by Pain! is the inspirational, true story of a mother and daughter’s 14-year journey for a cure to an agonizing and often misdiagnosed, debilitating disease known as adhesions. Melissa Steward was like any other happy, bubbly teen before illness struck at the age of 13. Doctors gave a diagnosis of Crohn’s disease and prescribed corticosteroids as treatment. However, the powerful drugs proved futile against the constant pain, nausea and vomiting that tortured the teen day after day. Believing her daughter had been misdiagnosed, Karen set out on her never-ending quest for an answer. Karen relates the riveting tale of their desperate cry for help and ultimate triumphant journey transversing the globe. Along the way, she provides a glimpse into the inner sanctum and frustrating maze of modern medicine.

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http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12777291-adhesion-pain