New Drug May Treat Constipation Caused by Strong Painkillers


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New Drug May Treat Constipation Caused by Strong Painkillers

A new drug holds promise as a safe and effective treatment for constipation caused by prescription narcotic painkillers, new research states.

Constipation is a common side effect experienced by patients taking these powerful medications for chronic pain. When laxatives failed to provide relief, two phase 3 trials found the once-daily drug naloxegol could help.

“The studies showed rapid and sustained improvement for these patients, without compromising their pain management,” study author Dr. William Chey, a gastroenterologist and professor of internal medicine at the University of Michigan Health System, said in a university news release.  To read more please go to this link:

http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12936291-new-drug-may-treat-constipation-caused-by-strong-painkillers

Pain Expert B. Eliot Cole, MD, Explains Why Patients Have to Fight for Good Care


Pain Expert B. Eliot Cole, MD, Explains Why Patients Have to Fight for Good Care

Q: Can a family doctor successfully treat chronic pain?

A: The view of most primary care doctors is that they treat all pain as acute pain, no matter how long it goes on. Acute pain should be thought of as ending in 30 days, then its subacute for 30 to 60 days, but after that its chronic pain. The biology of chronic pain is not the biology of acute pain. If you fall and break your wrist, the bones will heal within four to six weeks, but pain may continue. You cant treat that like you would the acute fracture.

To read more please go to this link:

http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12936118-pain-expert-b-eliot-cole-md-explains-why-patients-have-to-fight-for-good-care

OFF-LABEL PHARMACEUTICAL USE


OFF-LABEL PHARMACEUTICAL USE
According to NIH, there are almost 7,000 identified distinct rare diseases, the vast majority of which are genetic in nature. The Orphan Drug Act of 1983 has been a landmark success at making the development of orphan products a profitable venture, thereby driving industry to invest in research and development for rare disease treatments. To date, some 2,200 investigational therapies have been designated “orphan drugs” by FDA’s Office of Orphan Products Development, and 360 of these have gone on through the review process to be approved for marketing.
The approval of 360 drugs is a huge step in the right direction for the rare disease community. However, these drugs are indicated for only about 200 rare diseases, leaving approximately 6,800 diseases without FDA-approved treatment. In other words,

To read more please go to:
http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12780050-off-label-pharmaceutical-use

10 Key Questions About Migraines What Is a Migraine?


10 Key Questions About Migraines What Is a Migraine?

Migraine is a type of headache that is often localized in a certain area of the head and is sometimes accompanied by a pronounced sensitivity to light and sound. Other common migraine symptoms include nausea and vomiting. Migraines are usually gradual in onset, progressively more painful and then undergo a gradual resolution. When migraines are mild to moderate, they are usually described as being dull, deep and steady. When severe, migraines are throbbing or pulsating.
Some migraines are worsened by head motion, sneezing, straining or physical exertion. Since many patients also become sensitive to light and sound, some migraine sufferers will lie down in a darkened and quiet room to relieve symptoms. To Read more please click on this link:
http://www.chronicintractablepainandyou.net/apps/forums/topics/show/12918033-10-key-questions-about-migraines